PodcastMark Hyman Podcast
One Dose That Heals Addiction, PTSD, and Brain Injury — The Science of Ibogaine
Dr. Mark Hyman's podcast on functional medicine brought ibogaine to a broad mainstream health audience, examining the mechanisms through which a single ibogaine experience can interrupt years of addiction and address PTSD symptoms that have not responded to conventional treatment. The episode covers the pharmacology, the risks, and the genuine therapeutic potential in a way that bridges the gap between plant medicine communities and evidence-based medical audiences.
Watch on YouTubeTED TalkTED Talk — Nolan Williams, MD
How Ibogaine Could Treat Depression and Anxiety
Dr. Nolan Williams, a Stanford psychiatrist and neuroscientist, presents the scientific case for ibogaine as a treatment for depression and anxiety. Drawing on his research with special operations veterans, Williams explains how ibogaine differs mechanistically from other antidepressants and why its effects persist long after the compound has cleared the body. One of the clearest scientific explanations of ibogaine's therapeutic potential from a credentialed academic voice.
Watch on YouTubePodcastAndrew Huberman Podcast
Treating Depression & PTSD with Ibogaine & DMT — DJ Shipley
Neuroscientist and Stanford professor Andrew Huberman hosts a conversation with DJ Shipley — a former Navy SEAL — about his personal experience with ibogaine and 5-MeO-DMT. Shipley describes the neurological and psychological effects from the inside, and Huberman provides the scientific context. The episode introduced ibogaine to a significant new audience and is notable for its careful, sober approach to a topic that is often discussed with either breathless enthusiasm or reflexive scepticism.
Watch on YouTubeDocumentaryShort Film
Psychedelic Assisted Recovery — Therapy for Addiction Recovery
A documentary short exploring ibogaine as a treatment for addiction recovery. The film follows several individuals through the process — from the decision to pursue treatment through ceremony and into the integration period. Notable for showing the difficulty of the experience alongside its outcomes, rather than presenting a sanitised version of a journey that is genuinely demanding.
Watch on YouTubeResearchPubMed — Clinical Pharmacology Study
The Clinical Pharmacology and Potential Therapeutic Applications of 5-MeO-DMT
Significant reductions in depression, anxiety, stress and increases in life satisfaction, mindfulness
A peer-reviewed study published on PubMed examining the pharmacological profile of 5-MeO-DMT and its therapeutic applications. The research documented significant reductions in depression, anxiety, and stress among participants, alongside measurable increases in life satisfaction and mindfulness. This is one of the foundational academic references for understanding the therapeutic potential of 5-MeO-DMT beyond anecdote and into evidence-based medicine.
Read the studyPodcastJoe Rogan Experience
Treating Opioid Addiction with Ibogaine — Rick Perry's Crusade
Former Texas Governor Rick Perry discussed his advocacy for ibogaine treatment for veterans suffering from opioid addiction and PTSD. Perry's support played a significant role in moving ibogaine toward clinical research at the state level in Texas. The episode brought the political and legislative dimensions of ibogaine access to a mass audience — including the question of why a treatment with this level of evidence remains outside approved medical use.
Watch on YouTubeResearchTexas Clinical Trials
$50 Million State Investment in Ibogaine Research
$50 million USD committed. UTMB, UTHealth Houston, Texas A&M, Baylor University
The state of Texas committed $50 million USD to fund clinical trials of ibogaine for addiction treatment and PTSD, involving four major research institutions: UTMB (University of Texas Medical Branch), UTHealth Houston, Texas A&M, and Baylor University. This represents one of the largest state-level investments in psychedelic medicine research in history, and signals a significant shift in how institutional medicine is approaching ibogaine.
Read the announcementResearchStanford University — Nature Medicine
PTSD Symptoms Decreased 88%, Depression 87%, Anxiety 81%
PTSD −88% · Depression −87% · Anxiety −81% at one month post-treatment
Published in Nature Medicine in 2023, this Stanford study examined ibogaine treatment in special operations veterans with significant trauma histories, TBI (traumatic brain injury), and treatment-resistant depression. The results were striking enough to shift the conversation in mainstream medicine. Researchers measured outcomes at one month post-treatment and found PTSD symptoms decreased by 88%, depression symptoms decreased by 87%, and anxiety symptoms decreased by 81%. The study has been cited extensively in subsequent research and policy discussions.
Read the studyDocumentaryNetflix — November 2025
In Waves and War
A documentary exploring ibogaine treatment among military veterans with PTSD and addiction. Premiering on Netflix in November 2025, the film documents multiple veterans through the treatment process — the preparation, the ceremony, and the integration period that follows. The film's distribution on Netflix represents a significant cultural moment for ibogaine: a substance that has been in therapeutic use for decades but is only now entering mainstream awareness.
Watch trailer on YouTube